Raised by their loving and eccentric uncle Django, the McCable sisters assume their early thirties will be a time of happiness and stability. However, Cat, the youngest, is home from abroad to begin a new phase of her life - but it's proving more difficult than she thought. Fen is determined to be a better mother to her baby than her own was to her - though her love-life is suffering as a result. Pip, the eldest, loves looking after her stepson, her husband, her uncle and her sisters - even if her own needs are sidelined. At Django's 75th birthday party, secrets are revealed that throw the family into chaos. Can heart and home ever be reconciled for the McCabes? After all, what does it mean if suddenly your sisters aren't quite your sisters?